Your contact partners
in this area:
Univ. Prof. <br/> Dr. med. Raimund W. Kinne
Univ. Prof.
Dr. med. Raimund W. Kinne

Telephone:
036691 8-1228


Implant research

Implant structures in combination with growth factors

With advancing age of recipients of artificial joints, the need for biologically optimised implant materials increases, as healing and regeneration of the bone decreases considerably with old age and therefore the implant itself should offer support for the healing process.

The identification of specific bone growth factors means that these factors are now also available as molecular-biologically produced preparations. So far, however, there is little experience in the use of these preparations.
 
Therefore we carry out exemplary research on aged and osteoporotic animals as to how these bone growth factors can improve the healing process. For example, in a series of tests we were able to prove that the factors BMP-2 and GDF-5 on model implants considerably improve bone healing on aged sheep.
 
Publications
Sachse A, et al. "Osteo-integration of hydroxyapatite-titanium implants coated with non-glycosylated recombinant human bone morphogenetic protein-2 (BMP-2) in aged sheep". Bone (in press).

This may interest you:
Orthopaedics: Sports injuries and shoulder disorders
Autologous chondrocyte transplantation

Autologous chondrocyte transplantation on the knee joint is a biological procedure used on cartilage defects and which in the long term can eliminate the need for replacement of the knee joint.

More information.


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Implant without bone growth factor

Implant without bone growth factor

Implant with bone growth factor

Implant with bone growth factor